منابع مشابه
Metabolism of the Steroid Hormones
The biological relationship between ac-estradiol and estrone has been established by the isolation of the latter compound from the urine of normal and ovariectomized female and normal male guinea pigs (2, 3) and man (4,5) following the administration of cu-estradiol. In view of the conclusion of Pincus (6), that a-estradiol is not converted to estrone by the ovariectomized rabbit, it was consid...
متن کاملSteroid Hormones: Membrane transporters of steroid hormones
The discovery of a plasma membrane ABC protein that exports steroids in yeast highlights the possibility that similar membrane sorting systems in mammalian cells may modulate the access of steroids to their receptors.
متن کاملThe Role of Steroid Hormones in Skeletal Muscle Metabolism
Steroid hormones play important roles in the regulation of whole body metabolism. Skeletal muscle is an insulin-responsive organ with a key role in overall substrate metabolism. Disturbances in skeletal muscle metabolism, as a result of hormonal imbalance may be an underlying defect in metabolic disease. Reduced insulin-responsive glucose disposal in skeletal muscle is a characteristic feature ...
متن کاملBiosynthesis and metabolism of steroid hormones by human adrenal carcinomas.
Over a 15-year period, our university-based laboratory obtained 125 adrenal tumors, of which 15 (12%) were adrenal cortical carcinomas. Of these, 6 (40% of the carcinomas) occurred in patients with clear clinical manifestations of steroid hormone excess. Adrenal cortical carcinoma cells derived from the surgically resected tumors in 4 of these patients were isolated and established in primary c...
متن کاملThe Steroid Hormones in Pregnancy
THE marked changes in hormone production in pregnancy are associated with changes in metabolism and function. Much of the work which has been done and is being continued in the Clinical Research Unit of this department is concerned with the changes in body composition in normal and abnormal pregnancy and the puerperium and in the uterine activity in la;bour. The earlier endocrine work had been ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1944
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)43188-2